Matthew Brown

Work

University of Florida

|

Biological Scientist II - UF Diabetes Institute

US

→

Education

University of Florida

United States of America
→
MD/PhD

University of Florida

United States of America
→
Bachelors of Interdisciplinary Studies - Biochemistry & Molecular Biology

Publications

Human Stem Cell-Derived β-cells Expressing An Optimized CD155 Reduce Cytotoxic Immune Cell Function for Application in Type 1 Diabetes

preprint

Leveraging artificial intelligence and machine learning to accelerate discovery of disease-modifying therapies in type 1 diabetes

Diabetologia

journal-article

Inhibition of CD226 co-stimulation suppresses diabetes development in the NOD mouse by augmenting regulatory T cells and diminishing effector T cell function

Diabetologia

journal-article

Treg-Specific CD226 Deletion Reduces Diabetes Incidence in NOD Mice by Improving Regulatory T-Cell Stability

Diabetes

journal-article

Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells

The Journal of Immunology

journal-article

Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8+ T cells

Frontiers in Immunology

journal-article

Human CD4+CD25+CD226- Tregs Demonstrate Increased Purity, Lineage Stability, and Suppressive Capacity Versus CD4+CD25+CD127lo/- Tregs for Adoptive Cell Therapy

Frontiers in immunology

journal-article

The Immunoregulatory Role of the Signal Regulatory Protein Family and CD47 Signaling Pathway in Type 1 Diabetes

Frontiers in immunology

journal-article

192-LB: Human CD4+CD25+CD226- Regulatory T Cells Demonstrate High Purity and Lineage Stability following In Vitro Expansion for Adoptive Cell Therapy

Diabetes

journal-article